Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM301083'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301083 (4-[2-(4-aminopiperidin-1-yl)-5-(2- methylpyrazolo[...) Show SMILES Cn1cc2ncc(cc2n1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC(N)CC1 Show InChI InChI=1S/C23H22N8/c1-30-14-21-20(29-30)10-17(12-26-21)19-13-27-23(31-8-6-18(25)7-9-31)28-22(19)16-4-2-15(11-24)3-5-16/h2-5,10,12-14,18H,6-9,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
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