Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM301087'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301087 (4-[2-(4-aminopiperidin-1-yl)-5-[1- (2,2,2-trifluor...) Show SMILES NC1CCN(CC1)c1ncc(-c2cnn(CC(F)(F)F)c2)c(n1)-c1ccc(C#N)c(F)c1 Show InChI InChI=1S/C21H19F4N7/c22-18-7-13(1-2-14(18)8-26)19-17(15-9-29-32(11-15)12-21(23,24)25)10-28-20(30-19)31-5-3-16(27)4-6-31/h1-2,7,9-11,16H,3-6,12,27H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair