Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysosomal acid lipase/cholesteryl ester hydrolase' and Ligand = 'BDBM50287473'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid lipase/cholesteryl ester hydrolase (Homo sapiens (Human))	BDBM50287473 (3,3,4,4,4-Pentafluoro-1-((2S,4aS,8aS)-4a-methyl-de...) Show SMILES C[C@@]12CCCC[C@H]1C[C@@H](CC(=O)C(F)(F)C(F)(F)F)CC2 Show InChI InChI=1S/C15H21F5O/c1-13-6-3-2-4-11(13)8-10(5-7-13)9-12(21)14(16,17)15(18,19)20/h10-11H,2-9H2,1H3/t10-,11-,13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ancreatic cholesterol esterase using using p-nitrophenylacetate or cholesteryl [1-14C]-oleate as substrates				Bioorg Med Chem Lett 6: 1673-1676 (1996) Article DOI: 10.1016/0960-894X(96)00290-9 BindingDB Entry DOI: 10.7270/Q2H70FSC
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