Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysosomal acid lipase/cholesteryl ester hydrolase' and Ligand = 'BDBM50318692'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid lipase/cholesteryl ester hydrolase (Homo sapiens (Human))	BDBM50318692 (4-(Pyrrolidin-1-yl)-1,2,5-thiadiazol-3-yl morpholi...) Show SMILES O=C(Oc1nsnc1N1CCCC1)N1CCOCC1 Show InChI InChI=1S/C11H16N4O3S/c16-11(15-5-7-17-8-6-15)18-10-9(12-19-13-10)14-3-1-2-4-14/h1-8H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	473	n/a	n/a	n/a	n/a	n/a	n/a
Weill Cornell Medical College Curated by ChEMBL					Assay Description Inhibition of human LAL after 30 mins by fluorescence assay				J Med Chem 53: 5281-9 (2010) Article DOI: 10.1021/jm100499s BindingDB Entry DOI: 10.7270/Q2FB53XB
					More data for this Ligand-Target Pair