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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP/microtubule affinity-regulating kinase 2' and Ligand = 'BDBM50218700'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP/microtubule affinity-regulating kinase 2


(Homo sapiens (Human))
BDBM50218700
PNG
(2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydr...)
Show SMILES COc1cc(ccc1N)-c1ccc2c(Nc3ccc(CC(=O)Nc4ccc(cc4)N4CCOCC4)cc3NC2=O)c1
Show InChI InChI=1S/C32H31N5O4/c1-40-30-19-22(4-10-26(30)33)21-3-9-25-28(18-21)35-27-11-2-20(16-29(27)36-32(25)39)17-31(38)34-23-5-7-24(8-6-23)37-12-14-41-15-13-37/h2-11,16,18-19,35H,12-15,17,33H2,1H3,(H,34,38)(H,36,39)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.39E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of recombinant EMK by radiometric assay


J Med Chem 50: 4162-76 (2007)


Article DOI: 10.1021/jm070105d
More data for this
Ligand-Target Pair