Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2' and Ligand = 'BDBM50348503'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50348503 (CHEMBL1801280) Show SMILES O=C1NC2(CC2)Cc2[nH]c-3c(CCc4cnc(cc-34)-c3ccc(OCCN4CCOCC4)cc3)c12 Show InChI InChI=1S/C28H30N4O3/c33-27-25-21-6-3-19-17-29-23(15-22(19)26(21)30-24(25)16-28(31-27)7-8-28)18-1-4-20(5-2-18)35-14-11-32-9-12-34-13-10-32/h1-2,4-5,15,17,30H,3,6-14,16H2,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of human MK2 using biotinyl-AYSRALSRQLSSGVSEIRCOOH as substrate after 45 mins by FRET analysis				Bioorg Med Chem Lett 20: 4719-23 (2010) Checked by Author Article DOI: 10.1016/j.bmcl.2010.04.023 BindingDB Entry DOI: 10.7270/Q2BZ66C2
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50348503 (CHEMBL1801280) Show SMILES O=C1NC2(CC2)Cc2[nH]c-3c(CCc4cnc(cc-34)-c3ccc(OCCN4CCOCC4)cc3)c12 Show InChI InChI=1S/C28H30N4O3/c33-27-25-21-6-3-19-17-29-23(15-22(19)26(21)30-24(25)16-28(31-27)7-8-28)18-1-4-20(5-2-18)35-14-11-32-9-12-34-13-10-32/h1-2,4-5,15,17,30H,3,6-14,16H2,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of MK2 mediated anisomycin-stimulated hsp27 phosphorylation in human THP-1 cells by fluorometric analysis				Bioorg Med Chem Lett 20: 4719-23 (2010) Checked by Author Article DOI: 10.1016/j.bmcl.2010.04.023 BindingDB Entry DOI: 10.7270/Q2BZ66C2
					More data for this Ligand-Target Pair