Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 5' and Ligand = 'BDBM50365785'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 5 (Homo sapiens (Human))	BDBM50365785 (CHEMBL1956564) Show SMILES NC(=O)c1ccc(cc1)-c1cnc(Nc2ccc(cc2)N2CCOCC2)c2nccn12 Show InChI InChI=1S/C23H22N6O2/c24-21(30)17-3-1-16(2-4-17)20-15-26-22(23-25-9-10-29(20)23)27-18-5-7-19(8-6-18)28-11-13-31-14-12-28/h1-10,15H,11-14H2,(H2,24,30)(H,26,27)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	914	n/a	n/a	n/a	n/a	n/a	n/a
Galapagos NV Curated by ChEMBL					Assay Description Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...				Bioorg Med Chem Lett 22: 2266-70 (2012) Article DOI: 10.1016/j.bmcl.2012.01.077 BindingDB Entry DOI: 10.7270/Q2CR5TT6
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 5 (Homo sapiens (Human))	BDBM50365785 (CHEMBL1956564) Show SMILES NC(=O)c1ccc(cc1)-c1cnc(Nc2ccc(cc2)N2CCOCC2)c2nccn12 Show InChI InChI=1S/C23H22N6O2/c24-21(30)17-3-1-16(2-4-17)20-15-26-22(23-25-9-10-29(20)23)27-18-5-7-19(8-6-18)28-11-13-31-14-12-28/h1-10,15H,11-14H2,(H2,24,30)(H,26,27)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Galapagos NV Curated by ChEMBL					Assay Description Inhibition of MAPKAPK5				Bioorg Med Chem Lett 22: 2266-70 (2012) Article DOI: 10.1016/j.bmcl.2012.01.077 BindingDB Entry DOI: 10.7270/Q2CR5TT6
					More data for this Ligand-Target Pair