Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 5' and Ligand = 'BDBM50365792'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 5 (Homo sapiens (Human))	BDBM50365792 (CHEMBL1956571) Show SMILES NC(=O)c1cnc(s1)-c1cnc(Nc2ccc(cc2)N2CCOCC2)c2nccn12 Show InChI InChI=1S/C20H19N7O2S/c21-17(28)16-12-24-20(30-16)15-11-23-18(19-22-5-6-27(15)19)25-13-1-3-14(4-2-13)26-7-9-29-10-8-26/h1-6,11-12H,7-10H2,(H2,21,28)(H,23,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Galapagos NV Curated by ChEMBL					Assay Description Inhibition of MAPKAPK5				Bioorg Med Chem Lett 22: 2266-70 (2012) Article DOI: 10.1016/j.bmcl.2012.01.077 BindingDB Entry DOI: 10.7270/Q2CR5TT6
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 5 (Homo sapiens (Human))	BDBM50365792 (CHEMBL1956571) Show SMILES NC(=O)c1cnc(s1)-c1cnc(Nc2ccc(cc2)N2CCOCC2)c2nccn12 Show InChI InChI=1S/C20H19N7O2S/c21-17(28)16-12-24-20(30-16)15-11-23-18(19-22-5-6-27(15)19)25-13-1-3-14(4-2-13)26-7-9-29-10-8-26/h1-6,11-12H,7-10H2,(H2,21,28)(H,23,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Galapagos NV Curated by ChEMBL					Assay Description Inhibition of MAPKAPK5 in syonovial fibroblast from rheumatoid arthritis patient assessed as inhibition of TNF-alpha-induced MMP1 expression incubate...				Bioorg Med Chem Lett 22: 2266-70 (2012) Article DOI: 10.1016/j.bmcl.2012.01.077 BindingDB Entry DOI: 10.7270/Q2CR5TT6
					More data for this Ligand-Target Pair