Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM168333'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168333 (US9669031, 169 6′-((6-amino-5-fluoropyrimidi...) Show SMILES Fc1c(NC(=O)C2CC2)ncnc1Nc1cc(Cl)c2C(=O)NC3(CCCCC3)n2c1=O Show InChI InChI=1S/C20H20ClFN6O3/c21-11-8-12(19(31)28-14(11)18(30)27-20(28)6-2-1-3-7-20)25-15-13(22)16(24-9-23-15)26-17(29)10-4-5-10/h8-10H,1-7H2,(H,27,30)(H2,23,24,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
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