Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM168368'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM168368 (US9669031, 220 6-((6-amino-5-methylpyrimidin-4-yl)...) Show SMILES CN1CCC2(CC1)NC(=O)c1c(C)cc(Nc3ncnc(NC(=O)C4CC4)c3C)c(=O)n21 Show InChI InChI=1S/C22H27N7O3/c1-12-10-15(25-17-13(2)18(24-11-23-17)26-19(30)14-4-5-14)21(32)29-16(12)20(31)27-22(29)6-8-28(3)9-7-22/h10-11,14H,4-9H2,1-3H3,(H,27,31)(H2,23,24,25,26,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
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