Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM27889'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM27889 (8-(2,3-dihydro-1H-inden-5-yl)-2-{[4-(4-methylpiper...) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(cc(C(N)=O)c3=O)-c2ccc3CCCc3c2)cc1 Show InChI InChI=1S/C28H29N7O2/c1-33-11-13-34(14-12-33)21-9-6-20(7-10-21)31-28-30-16-23-25(36)24(26(29)37)17-35(27(23)32-28)22-8-5-18-3-2-4-19(18)15-22/h5-10,15-17H,2-4,11-14H2,1H3,(H2,29,37)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	22
Johnson & Johnson Pharmaceutical					Assay Description FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...				J Med Chem 52: 1081-99 (2009) Article DOI: 10.1021/jm801406h BindingDB Entry DOI: 10.7270/Q21834T7
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM27889 (8-(2,3-dihydro-1H-inden-5-yl)-2-{[4-(4-methylpiper...) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(cc(C(N)=O)c3=O)-c2ccc3CCCc3c2)cc1 Show InChI InChI=1S/C28H29N7O2/c1-33-11-13-34(14-12-33)21-9-6-20(7-10-21)31-28-30-16-23-25(36)24(26(29)37)17-35(27(23)32-28)22-8-5-18-3-2-4-19(18)15-22/h5-10,15-17H,2-4,11-14H2,1H3,(H2,29,37)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of CSF1R				Bioorg Med Chem Lett 18: 2355-61 (2008) Article DOI: 10.1016/j.bmcl.2008.02.070 BindingDB Entry DOI: 10.7270/Q26W9BX3
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human))	BDBM27889 (8-(2,3-dihydro-1H-inden-5-yl)-2-{[4-(4-methylpiper...) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(cc(C(N)=O)c3=O)-c2ccc3CCCc3c2)cc1 Show InChI InChI=1S/C28H29N7O2/c1-33-11-13-34(14-12-33)21-9-6-20(7-10-21)31-28-30-16-23-25(36)24(26(29)37)17-35(27(23)32-28)22-8-5-18-3-2-4-19(18)15-22/h5-10,15-17H,2-4,11-14H2,1H3,(H2,29,37)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of ATP-induced CSF1R autophosphorylation				Bioorg Med Chem Lett 18: 2355-61 (2008) Article DOI: 10.1016/j.bmcl.2008.02.070 BindingDB Entry DOI: 10.7270/Q26W9BX3
					More data for this Ligand-Target Pair