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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50121690'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50121690
PNG
(CHEMBL3616960)
Show SMILES CN1CCN(CC1)c1cc(cc(c1)C(F)(F)F)C(=O)Nc1ccc(C)c(NC(=O)c2cnoc2C)c1
Show InChI InChI=1S/C25H26F3N5O3/c1-15-4-5-19(13-22(15)31-24(35)21-14-29-36-16(21)2)30-23(34)17-10-18(25(26,27)28)12-20(11-17)33-8-6-32(3)7-9-33/h4-5,10-14H,6-9H2,1-3H3,(H,30,34)(H,31,35)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 10n/an/an/an/an/an/a



Hanyang University

Curated by ChEMBL


Assay Description
Inhibition of FMS (unknown origin) after 40 mins by scintillation counting analysis


Eur J Med Chem 102: 600-10 (2015)


BindingDB Entry DOI: 10.7270/Q2XG9SXV
More data for this
Ligand-Target Pair