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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50321370'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50321370
PNG
(4-Cyano-1H-imidazole-2-carboxylicacid[2-cyclohex-1...)
Show SMILES O=C(Nc1ccc(cc1C1=CCCCC1)C1CNS(=O)(=O)NC1)c1ncc([nH]1)C#N |t:10|
Show InChI InChI=1S/C20H22N6O3S/c21-9-16-12-22-19(25-16)20(27)26-18-7-6-14(15-10-23-30(28,29)24-11-15)8-17(18)13-4-2-1-3-5-13/h4,6-8,12,15,23-24H,1-3,5,10-11H2,(H,22,25)(H,26,27)
PDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Inhibition of human FMS by fluorescence polarization


Bioorg Med Chem Lett 20: 3925-9 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.013
BindingDB Entry DOI: 10.7270/Q22Z16HG
More data for this
Ligand-Target Pair