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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM50375155'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50375155
PNG
(CHEMBL256893)
Show SMILES CN1CCN(Cc2ccc(Nc3ncc4c(n3)n(cc(C(N)=O)c4=O)-c3ccc4CCCc4c3)cc2)CC1
Show InChI InChI=1S/C29H31N7O2/c1-34-11-13-35(14-12-34)17-19-5-8-22(9-6-19)32-29-31-16-24-26(37)25(27(30)38)18-36(28(24)33-29)23-10-7-20-3-2-4-21(20)15-23/h5-10,15-16,18H,2-4,11-14,17H2,1H3,(H2,30,38)(H,31,32,33)
PDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Inhibition of ATP-induced CSF1R autophosphorylation


Bioorg Med Chem Lett 18: 2355-61 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.070
BindingDB Entry DOI: 10.7270/Q26W9BX3
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50375155
PNG
(CHEMBL256893)
Show SMILES CN1CCN(Cc2ccc(Nc3ncc4c(n3)n(cc(C(N)=O)c4=O)-c3ccc4CCCc4c3)cc2)CC1
Show InChI InChI=1S/C29H31N7O2/c1-34-11-13-35(14-12-34)17-19-5-8-22(9-6-19)32-29-31-16-24-26(37)25(27(30)38)18-36(28(24)33-29)23-10-7-20-3-2-4-21(20)15-23/h5-10,15-16,18H,2-4,11-14,17H2,1H3,(H2,30,38)(H,31,32,33)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Inhibition of CSF1R


Bioorg Med Chem Lett 18: 2355-61 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.070
BindingDB Entry DOI: 10.7270/Q26W9BX3
More data for this
Ligand-Target Pair