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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage-expressed gene 1 protein' and Ligand = 'BDBM50078878'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage-expressed gene 1 protein


(Homo sapiens (Human))
BDBM50078878
PNG
(CHEMBL3416169)
Show SMILES CCCCC1=C(O)C(=O)C=C(OC)C1=O |c:4,t:9|
Show InChI InChI=1S/C11H14O4/c1-3-4-5-7-10(13)8(12)6-9(15-2)11(7)14/h6,13H,3-5H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Naples

Curated by ChEMBL


Assay Description
Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ...


Eur J Med Chem 94: 132-9 (2015)


Article DOI: 10.1016/j.ejmech.2015.02.042
More data for this
Ligand-Target Pair