Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM193951'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM193951 (US9199981, F42) Show SMILES Cc1ccc(cc1NC(=O)c1cnc2ccc(cn12)-c1cnn(C)c1)-c1noc(n1)C1CC(F)(F)C1 Show InChI InChI=1S/C25H21F2N7O2/c1-14-3-4-15(22-31-24(36-32-22)17-8-25(26,27)9-17)7-19(14)30-23(35)20-11-28-21-6-5-16(13-34(20)21)18-10-29-33(2)12-18/h3-7,10-13,17H,8-9H2,1-2H3,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description The compounds was tested for inhibition of SCF dependent proliferation using human Mo7e cells which endogenously express c-kit in a 384 well format. ...				US Patent US9199981 (2015) BindingDB Entry DOI: 10.7270/Q2M32TKJ
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