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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit' and Ligand = 'BDBM50152685'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))		BDBM50152685
PNG
(CHEMBL3780676)
Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(Cl)c5ccccc5n(-c5ccc(F)cc5)c4=O)cc3F)ccnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C40H36ClF2N5O5/c1-46-17-19-47(20-18-46)16-5-21-52-36-24-31-29(23-35(36)51-2)33(14-15-44-31)53-34-13-10-26(22-30(34)43)45-39(49)37-38(41)28-6-3-4-7-32(28)48(40(37)50)27-11-8-25(42)9-12-27/h3-4,6-15,22-24H,5,16-21H2,1-2H3,(H,45,49)
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Similars
Article
PubMed
n/an/a 363n/an/an/an/an/an/a



Jiangxi Science and Technology Normal University

Curated by ChEMBL


Assay Description
Inhibition of cKIT (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay

Bioorg Med Chem Lett 26: 1794-8 (2016)


Article DOI: 10.1016/j.bmcl.2016.02.037
BindingDB Entry DOI: 10.7270/Q2TT4ST4
More data for this
Ligand-Target Pair