Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50381716 (ABT-348 | ILORASERTIB | US8722890, 1 | US8722890, ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 19.5 | n/a | n/a | n/a | n/a | 7.1 | 25 |
AbbVie Inc. US Patent | Assay Description To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)... | US Patent US8722890 (2014) BindingDB Entry DOI: 10.7270/Q21Z4327 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50381716 (ABT-348 | ILORASERTIB | US8722890, 1 | US8722890, ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 27.3 | n/a | n/a | n/a | n/a | 7.1 | 25 |
AbbVie Inc. US Patent | Assay Description To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)... | US Patent US8722890 (2014) BindingDB Entry DOI: 10.7270/Q21Z4327 | |||||||||||
More data for this Ligand-Target Pair |