Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM50235401'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50235401 (CHEMBL4071823) Show SMILES COc1ccc2nc(CNC(=O)c3ccc(cc3)-c3cnccc3OCC3CCNCC3)[nH]c2c1 Show InChI InChI=1S/C27H29N5O3/c1-34-21-6-7-23-24(14-21)32-26(31-23)16-30-27(33)20-4-2-19(3-5-20)22-15-29-13-10-25(22)35-17-18-8-11-28-12-9-18/h2-7,10,13-15,18,28H,8-9,11-12,16-17H2,1H3,(H,30,33)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of MELK (unknown origin) containing kinase domain and UBA domain using STK S1 as substrate after 20 mins by HTRF assay				J Med Chem 60: 2155-2161 (2017) Article DOI: 10.1021/acs.jmedchem.7b00033 BindingDB Entry DOI: 10.7270/Q2MC928T
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