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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-25' and Ligand = 'BDBM50346798'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-25


(Homo sapiens (Human))
BDBM50346798
PNG
(CHEMBL1795857)
Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO |r|
Show InChI InChI=1S/C32H32N2O5S2/c1-2-3-7-24-10-12-25(13-11-24)16-19-29-20-21-31(40-29)41(37,38)34-30(32(35)33-36)22-26-14-17-28(18-15-26)39-23-27-8-5-4-6-9-27/h4-6,8-15,17-18,20-21,30,34,36H,2-3,7,22-23H2,1H3,(H,33,35)/t30-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 38n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human MMP25 by fluorometric assay


Eur J Med Chem 46: 2617-29 (2011)


Article DOI: 10.1016/j.ejmech.2011.03.033
More data for this
Ligand-Target Pair