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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-25' and Ligand = 'BDBM50346800'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-25


(Homo sapiens (Human))
BDBM50346800
PNG
(CHEMBL1795859)
Show SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NO |r|
Show InChI InChI=1S/C27H27N3O4S2/c1-2-3-6-19-9-11-20(12-10-19)13-14-22-15-16-26(35-22)36(33,34)30-25(27(31)29-32)17-21-18-28-24-8-5-4-7-23(21)24/h4-5,7-12,15-16,18,25,28,30,32H,2-3,6,17H2,1H3,(H,29,31)/t25-/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 76n/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human MMP25 by fluorometric assay


Eur J Med Chem 46: 2617-29 (2011)


Article DOI: 10.1016/j.ejmech.2011.03.033
More data for this
Ligand-Target Pair