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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor' and Ligand = 'BDBM50199257'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50199257
PNG
(6-(4-chlorophenyl)-3-[6-(1-piperidinylmethyl)-5,6,...)
Show SMILES Clc1ccc(cc1)-c1cc2ncn(-c3ccc4CC(CN5CCCCC5)CCc4c3)c(=O)c2s1
Show InChI InChI=1S/C28H28ClN3OS/c29-23-9-6-20(7-10-23)26-16-25-27(34-26)28(33)32(18-30-25)24-11-8-21-14-19(4-5-22(21)15-24)17-31-12-2-1-3-13-31/h6-11,15-16,18-19H,1-5,12-14,17H2
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PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3.10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay


J Med Chem 49: 7108-18 (2006)


Article DOI: 10.1021/jm060814b
BindingDB Entry DOI: 10.7270/Q2JD4WFT
More data for this
Ligand-Target Pair