BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50295690'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50295690 ((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Binding affinity to human MCH1R expressed in CHO cells by scintillation counting per mg of protein				Bioorg Med Chem Lett 19: 2835-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.102 BindingDB Entry DOI: 10.7270/Q2R49QS7
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50295690 ((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...				Bioorg Med Chem Lett 19: 2835-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.102 BindingDB Entry DOI: 10.7270/Q2R49QS7
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Mus musculus)	BDBM50295690 ((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...				Bioorg Med Chem Lett 19: 2835-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.102 BindingDB Entry DOI: 10.7270/Q2R49QS7
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50295690 ((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of[125I]MCH from human MCH1R expressed in CHO cells				Bioorg Med Chem Lett 19: 2835-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.102 BindingDB Entry DOI: 10.7270/Q2R49QS7
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50295690 ((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCH1R expressed in CHO cells				Bioorg Med Chem Lett 19: 5339-45 (2009) Article DOI: 10.1016/j.bmcl.2009.07.132 BindingDB Entry DOI: 10.7270/Q27P90BK
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50295690 ((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of[125I]MCH from human MCH1R expressed in CHO cells				Bioorg Med Chem Lett 19: 2835-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.102 BindingDB Entry DOI: 10.7270/Q2R49QS7
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50295690 ((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of[125I]MCH from human MCH1R expressed in CHO cells				Bioorg Med Chem Lett 19: 2835-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.102 BindingDB Entry DOI: 10.7270/Q2R49QS7
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50295690 ((+/-)-2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluor...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human MCH1R expressed in CHO cells assessed as inhibition of MCH-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 2835-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.102 BindingDB Entry DOI: 10.7270/Q2R49QS7
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair