Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50139045'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50139045 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES CS(=O)(=O)NCc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C31H36ClN5O4S/c1-42(40,41)34-21-25-8-4-5-9-29(25)36-14-16-37(17-15-36)31(39)28(18-22-10-12-26(32)13-11-22)35-30(38)27-19-23-6-2-3-7-24(23)20-33-27/h2-13,27-28,33-34H,14-21H2,1H3,(H,35,38)/t27-,28-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP release				J Med Chem 47: 744-55 (2004) Article DOI: 10.1021/jm0304109 BindingDB Entry DOI: 10.7270/Q2DJ5F21
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50139045 (1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...) Show SMILES CS(=O)(=O)NCc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1 Show InChI InChI=1S/C31H36ClN5O4S/c1-42(40,41)34-21-25-8-4-5-9-29(25)36-14-16-37(17-15-36)31(39)28(18-22-10-12-26(32)13-11-22)35-30(38)27-19-23-6-2-3-7-24(23)20-33-27/h2-13,27-28,33-34H,14-21H2,1H3,(H,35,38)/t27-,28-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Agonistic potency of the compound towards human melanocortin 4 receptor, determined by 50% maximum cAMP release				J Med Chem 47: 744-55 (2004) Article DOI: 10.1021/jm0304109 BindingDB Entry DOI: 10.7270/Q2DJ5F21
					More data for this Ligand-Target Pair