Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50181498'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184A expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R I291A expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	275	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268F expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	305	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from human wild type MC4R expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287F expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268A expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184L expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R I125A expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287A expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from mutant MC4R I129A expressed in HEK293 cells				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R I129A expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9.5	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R I125A expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.02	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R Y268A expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R I291A expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.60	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	418	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R Y287A expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50181498 ((4-((1H-1,2,4-triazol-1-yl)methyl)-4-cyclohexylpip...) Show SMILES CN(C)[C@H]1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C28H40ClN5O/c1-32(2)24-16-25(21-8-10-23(29)11-9-21)26(17-24)27(35)33-14-12-28(13-15-33,18-34-20-30-19-31-34)22-6-4-3-5-7-22/h8-11,19-20,22,24-26H,3-7,12-18H2,1-2H3/t24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at the mutant MC4R F184L expressed in HEK293 cells by cAMP accumulation				J Med Chem 49: 911-22 (2006) Article DOI: 10.1021/jm050780s BindingDB Entry DOI: 10.7270/Q2D21ZCX
					More data for this Ligand-Target Pair