Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50245413'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245413 ((R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-m...) Show SMILES CC(C)CC(=O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CCN |r| Show InChI InChI=1S/C27H34Cl2N4O3/c1-18(2)15-25(34)21-5-3-4-6-24(21)32-11-13-33(14-12-32)27(36)23(31-26(35)9-10-30)16-19-7-8-20(28)17-22(19)29/h3-8,17-18,23H,9-16,30H2,1-2H3,(H,31,35)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to human MC4 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245413 ((R)-3-amino-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-m...) Show SMILES CC(C)CC(=O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CCN |r| Show InChI InChI=1S/C27H34Cl2N4O3/c1-18(2)15-25(34)21-5-3-4-6-24(21)32-11-13-33(14-12-32)27(36)23(31-26(35)9-10-30)16-19-7-8-20(28)17-22(19)29/h3-8,17-18,23H,9-16,30H2,1-2H3,(H,31,35)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human MC4 receptor expressed in cells assessed as inhibition of alpha-MSH-stimulated cAMP production				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
					More data for this Ligand-Target Pair