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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocyte-stimulating hormone receptor' and Ligand = 'BDBM250653'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM250653
PNG
(US9447148, 9.22)
Show SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCC(=O)NCC[C@H](NC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)NC(=O)CC1CCCCC1 |r|
Show InChI InChI=1/C49H66N14O8/c50-43(66)38(24-31-26-56-34-15-8-7-14-33(31)34)61-46(69)37-19-21-54-41(64)18-17-36(58-42(65)23-30-12-5-2-6-13-30)45(68)63-40(25-32-27-53-28-57-32)48(71)62-39(22-29-10-3-1-4-11-29)47(70)59-35(44(67)60-37)16-9-20-55-49(51)52/h1,3-4,7-8,10-11,14-15,26-28,30,35-40,56H,2,5-6,9,12-13,16-25H2,(H2,50,66)(H,53,57)(H,54,64)(H,58,65)(H,59,70)(H,60,67)(H,61,69)(H,62,71)(H,63,68)(H4,51,52,55)/t35-,36-,37-,38-,39+,40-/s2
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.0100 -65.3n/an/an/an/an/a7.537



Palatin Technologies, Inc.

US Patent


Assay Description
A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...


US Patent US9447148 (2016)


BindingDB Entry DOI: 10.7270/Q2RJ4HD2
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM250653
PNG
(US9447148, 9.22)
Show SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCC(=O)NCC[C@H](NC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O)NC(=O)CC1CCCCC1 |r|
Show InChI InChI=1/C49H66N14O8/c50-43(66)38(24-31-26-56-34-15-8-7-14-33(31)34)61-46(69)37-19-21-54-41(64)18-17-36(58-42(65)23-30-12-5-2-6-13-30)45(68)63-40(25-32-27-53-28-57-32)48(71)62-39(22-29-10-3-1-4-11-29)47(70)59-35(44(67)60-37)16-9-20-55-49(51)52/h1,3-4,7-8,10-11,14-15,26-28,30,35-40,56H,2,5-6,9,12-13,16-25H2,(H2,50,66)(H,53,57)(H,54,64)(H,58,65)(H,59,70)(H,60,67)(H,61,69)(H,62,71)(H,63,68)(H4,51,52,55)/t35-,36-,37-,38-,39+,40-/s2
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.00400n/an/a7.537



Palatin Technologies, Inc.

US Patent


Assay Description
Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...


US Patent US9447148 (2016)


BindingDB Entry DOI: 10.7270/Q2RJ4HD2
More data for this
Ligand-Target Pair