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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melatonin receptor' and Ligand = 'BDBM50188424'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melatonin receptor


(Homo sapiens (Human))
BDBM50188424
PNG
(CHEMBL209711 | N-(2-[5-methoxy-1-methyl-1H-indol-3...)
Show SMILES COc1ccc2n(C)cc(c2c1)C1(CNC(C)=O)CC1
Show InChI InChI=1S/C16H20N2O2/c1-11(19)17-10-16(6-7-16)14-9-18(2)15-5-4-12(20-3)8-13(14)15/h4-5,8-9H,6-7,10H2,1-3H3,(H,17,19)
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
90n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]iodomelatonin from human recombinant MT2 receptor expressed in NIH3T3 cells


J Med Chem 49: 3509-19 (2006)


Article DOI: 10.1021/jm0512544
BindingDB Entry DOI: 10.7270/Q2JW8DJQ
More data for this
Ligand-Target Pair
Melatonin receptor


(Homo sapiens (Human))
BDBM50188424
PNG
(CHEMBL209711 | N-(2-[5-methoxy-1-methyl-1H-indol-3...)
Show SMILES COc1ccc2n(C)cc(c2c1)C1(CNC(C)=O)CC1
Show InChI InChI=1S/C16H20N2O2/c1-11(19)17-10-16(6-7-16)14-9-18(2)15-5-4-12(20-3)8-13(14)15/h4-5,8-9H,6-7,10H2,1-3H3,(H,17,19)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
176n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Displacement of 2-[125I]iodomelatonin from human recombinant MT1 receptor expressed in NIH3T3 cells


J Med Chem 49: 3509-19 (2006)


Article DOI: 10.1021/jm0512544
BindingDB Entry DOI: 10.7270/Q2JW8DJQ
More data for this
Ligand-Target Pair