Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Membrane-bound transcription factor site-1 protease' and Ligand = 'BDBM50216199'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane-bound transcription factor site-1 protease (Homo sapiens (Human))	BDBM50216199 (4-(2-aza-bicyclo[2.2.1]heptan-2-ylmethyl)-N-(2-met...) Show SMILES COc1ccccc1CCN(C1CCNC1)C(=O)c1ccc(CN2CC3CCC2C3)cc1 |w:11.11,25.27,28.29,TLB:22:23:27.26:29| Show InChI InChI=1S/C27H35N3O2/c1-32-26-5-3-2-4-22(26)13-15-30(25-12-14-28-17-25)27(31)23-9-6-20(7-10-23)18-29-19-21-8-11-24(29)16-21/h2-7,9-10,21,24-25,28H,8,11-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development-Groton Laboratories Curated by ChEMBL					Assay Description Inhibition of human S1P expressed in CHOK1 cells				Bioorg Med Chem Lett 17: 4411-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.031 BindingDB Entry DOI: 10.7270/Q26M36JG
					More data for this Ligand-Target Pair