Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Menin' and Ligand = 'BDBM152211'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Menin (Homo sapiens (Human))	BDBM152211 (BDBM152229 | US8993552, 1) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc3CCCCc3c12 |c:4| Show InChI InChI=1S/C19H25N5S2/c1-19(2)11-20-18(26-19)24-9-7-23(8-10-24)16-15-13-5-3-4-6-14(13)25-17(15)22-12-21-16/h12H,3-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description One potential limitation of the above FP assay is the risk of selection of compounds that may interfere with the FP assays and produce so called fals...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152211 (BDBM152229 | US8993552, 1) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc3CCCCc3c12 |c:4| Show InChI InChI=1S/C19H25N5S2/c1-19(2)11-20-18(26-19)24-9-7-23(8-10-24)16-15-13-5-3-4-6-14(13)25-17(15)22-12-21-16/h12H,3-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of FITC-MBM1 from menin (unknown origin) measured after 1 hr by fluorescence polarization assay				Bioorg Med Chem 26: 356-365 (2018) Article DOI: 10.1016/j.bmc.2017.11.045 BindingDB Entry DOI: 10.7270/Q2SQ92ZS
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152211 (BDBM152229 | US8993552, 1) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc3CCCCc3c12 |c:4| Show InChI InChI=1S/C19H25N5S2/c1-19(2)11-20-18(26-19)24-9-7-23(8-10-24)16-15-13-5-3-4-6-14(13)25-17(15)22-12-21-16/h12H,3-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152211 (BDBM152229 | US8993552, 1) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc3CCCCc3c12 |c:4| Show InChI InChI=1S/C19H25N5S2/c1-19(2)11-20-18(26-19)24-9-7-23(8-10-24)16-15-13-5-3-4-6-14(13)25-17(15)22-12-21-16/h12H,3-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair