Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50004863 ((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Curated by PDSP Ki Database | J Neurochem 75: 2590-601 (2000) Article DOI: 10.1046/j.1471-4159.2000.0752590.x BindingDB Entry DOI: 10.7270/Q2J67FGZ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50004863 ((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Compound was tested for the inhibition of Metabotropic glutamate receptor 1 | J Med Chem 41: 1641-50 (1998) Article DOI: 10.1021/jm970719q BindingDB Entry DOI: 10.7270/Q27945BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50004863 ((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a |
Université René Descartes-Paris V Curated by ChEMBL | Assay Description Agonist activity against Metabotropic glutamate receptor 1 expressed in HEK 293 cells was evaluated by measuring total inositol phosphate accumulatio... | J Med Chem 40: 3119-29 (1997) Article DOI: 10.1021/jm970207b BindingDB Entry DOI: 10.7270/Q200016Q | |||||||||||
More data for this Ligand-Target Pair |