Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50132797 (CHEMBL3634445) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGluR1 by calcium mobilization assay | Bioorg Med Chem Lett 25: 5107-10 (2015) Article DOI: 10.1016/j.bmcl.2015.10.013 BindingDB Entry DOI: 10.7270/Q20C4XKQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50132797 (CHEMBL3634445) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci... | Bioorg Med Chem Lett 26: 1869-72 (2016) Article DOI: 10.1016/j.bmcl.2016.03.031 BindingDB Entry DOI: 10.7270/Q2Z03B11 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50132797 (CHEMBL3634445) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Inhibition of bovine trypsin | Bioorg Med Chem Lett 25: 5107-10 (2015) Article DOI: 10.1016/j.bmcl.2015.10.013 BindingDB Entry DOI: 10.7270/Q20C4XKQ | |||||||||||
More data for this Ligand-Target Pair |