Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50224393'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50224393 (8-(4-chlorophenyl)-1h-imidazo[4'',5'':4',5']pyrido...) Show SMILES Clc1ccc(cc1)-n1cnc2c(sc3ncc4[nH]cnc4c23)c1=O Show InChI InChI=1S/C16H8ClN5OS/c17-8-1-3-9(4-2-8)22-7-21-13-11-12-10(19-6-20-12)5-18-15(11)24-14(13)16(22)23/h1-7H,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]9-Dimethylamino-3-(4-methoxy-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one from mGluR1 in rat cerebellum membrane				J Med Chem 50: 5550-3 (2007) Article DOI: 10.1021/jm070590c BindingDB Entry DOI: 10.7270/Q2D50MQX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50224393 (8-(4-chlorophenyl)-1h-imidazo[4'',5'':4',5']pyrido...) Show SMILES Clc1ccc(cc1)-n1cnc2c(sc3ncc4[nH]cnc4c23)c1=O Show InChI InChI=1S/C16H8ClN5OS/c17-8-1-3-9(4-2-8)22-7-21-13-11-12-10(19-6-20-12)5-18-15(11)24-14(13)16(22)23/h1-7H,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1a expressed in CHO cells assessed by measuring intracellular calcium by FLIPR assay				J Med Chem 50: 5550-3 (2007) Article DOI: 10.1021/jm070590c BindingDB Entry DOI: 10.7270/Q2D50MQX
					More data for this Ligand-Target Pair