Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM160805'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM160805 (US9682980, 8-Chloro-3-(cyclopropylmethyl)-7-(4-(2-...) Show SMILES Fc1ccccc1C1CCN(CC1)c1ncn2c(CC3CC3)nnc2c1Cl Show InChI InChI=1S/C20H21ClFN5/c21-18-19(23-12-27-17(11-13-5-6-13)24-25-20(18)27)26-9-7-14(8-10-26)15-3-1-2-4-16(15)22/h1-4,12-14H,5-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4	n/a	n/a	7.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...				US Patent US9682980 (2017) BindingDB Entry DOI: 10.7270/Q2J964JS
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