Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM222976'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM222976 (US9315518, 8-14) Show SMILES Cn1c2nc(ccc2n(CC(C)(C)C)c1=O)C1=CC2CN(CC2C1)C(=O)C1(O)CCC1 |t:18| Show InChI InChI=1S/C24H32N4O3/c1-23(2,3)14-28-19-7-6-18(25-20(19)26(4)22(28)30)15-10-16-12-27(13-17(16)11-15)21(29)24(31)8-5-9-24/h6-7,10,16-17,31H,5,8-9,11-14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	51.4	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The stimulation of [35S]-GTPγS binding is a common functional assay to monitor Gαi-coupled receptor in native and recombinant receptor memb...				US Patent US9315518 (2016) BindingDB Entry DOI: 10.7270/Q2G44P5C
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