Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50017243'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017243 (CHEMBL3287683 | US10099993, Compound 32) Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(C(O)=O)c(Cl)c2)c(C)c1O Show InChI InChI=1S/C23H27ClO6/c1-14(2)12-20(25)18-8-9-21(15(3)22(18)26)30-11-5-4-10-29-16-6-7-17(23(27)28)19(24)13-16/h6-9,13-14,26H,4-5,10-12H2,1-3H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	151	n/a	n/a	7.3	25
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				US Patent US10099993 (2018) BindingDB Entry DOI: 10.7270/Q2Z89FFP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50017243 (CHEMBL3287683 | US10099993, Compound 32) Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(C(O)=O)c(Cl)c2)c(C)c1O Show InChI InChI=1S/C23H27ClO6/c1-14(2)12-20(25)18-8-9-21(15(3)22(18)26)30-11-5-4-10-29-16-6-7-17(23(27)28)19(24)13-16/h6-9,13-14,26H,4-5,10-12H2,1-3H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	151	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...				J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9
					More data for this Ligand-Target Pair