BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50078237'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Rattus norvegicus)		BDBM50078237
PNG
(5-(2-Chloro-phenyl)-2-(2,6-dichloro-phenyl)-7-meth...)
Show SMILES CN(C)CCOC(=O)C1=C(C)N=C2SC(=CN2C1c1ccccc1Cl)c1c(Cl)cccc1Cl |c:8,14,t:11|
Show InChI InChI=1S/C24H22Cl3N3O2S/c1-14-20(23(31)32-12-11-29(2)3)22(15-7-4-5-8-16(15)25)30-13-19(33-24(30)28-14)21-17(26)9-6-10-18(21)27/h4-10,13,22H,11-12H2,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 2.00E+3n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of 1S,3R-ACPD (10 microM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cells

Bioorg Med Chem Lett 9: 1573-6 (1999)


BindingDB Entry DOI: 10.7270/Q2XS5TKC
More data for this
Ligand-Target Pair