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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50151472'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50151472
PNG
((1R,2R,3R,5R,6R)-2-Amino-3-[bis-(4-fluoro-phenyl)-...)
Show SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OC(c1ccc(F)cc1)c1ccc(F)cc1)[C@]2(F)C(O)=O)C(O)=O
Show InChI InChI=1S/C21H18F3NO5/c22-12-5-1-10(2-6-12)16(11-3-7-13(23)8-4-11)30-15-9-14-17(20(14,24)18(26)27)21(15,25)19(28)29/h1-8,14-17H,9,25H2,(H,26,27)(H,28,29)/t14-,15-,17+,20-,21+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.79n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]-MGS0008


J Med Chem 47: 4570-87 (2004)


Article DOI: 10.1021/jm0400294
BindingDB Entry DOI: 10.7270/Q2GH9HFK
More data for this
Ligand-Target Pair