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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50151488'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50151488
PNG
((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-pentafluorophe...)
Show SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1c(F)c(F)c(F)c(F)c1F)[C@]2(F)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H11F6NO5/c16-6-3(7(17)9(19)10(20)8(6)18)2-27-5-1-4-11(14(4,21)12(23)24)15(5,22)13(25)26/h4-5,11H,1-2,22H2,(H,23,24)(H,25,26)/t4-,5-,11+,14-,15+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.77n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]-MGS0008


J Med Chem 47: 4570-87 (2004)


Article DOI: 10.1021/jm0400294
BindingDB Entry DOI: 10.7270/Q2GH9HFK
More data for this
Ligand-Target Pair