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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50153748'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50153748
PNG
(1-(2-Hydroxy-4-{1-methyl-4-[4-(2H-tetrazol-5-yl)-p...)
Show SMILES CCCc1c(OC(C)CCCOc2ccc(cc2)-c2nnn[nH]2)ccc(C(C)=O)c1O
Show InChI InChI=1S/C23H28N4O4/c1-4-6-20-21(13-12-19(16(3)28)22(20)29)31-15(2)7-5-14-30-18-10-8-17(9-11-18)23-24-26-27-25-23/h8-13,15,29H,4-7,14H2,1-3H3,(H,24,25,26,27)
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PC cid
PC sid
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Similars
Article
PubMed
n/an/an/an/a 918n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration for binding to human metabotropic glutamate receptor 2 as determined by GTPgammaS assay

Bioorg Med Chem Lett 14: 5329-32 (2004)


Article DOI: 10.1016/j.bmcl.2004.08.020
BindingDB Entry DOI: 10.7270/Q21Z43W0
More data for this
Ligand-Target Pair