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Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50155698'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50155698
PNG
(1-{3-Bromo-2-hydroxy-4-[4-(pyridin-4-ylsulfanyl)-b...)
Show SMILES CC(C)CC(=O)c1ccc(OCCCCSc2ccncc2)c(Br)c1O
Show InChI InChI=1S/C20H24BrNO3S/c1-14(2)13-17(23)16-5-6-18(19(21)20(16)24)25-11-3-4-12-26-15-7-9-22-10-8-15/h5-10,14,24H,3-4,11-13H2,1-2H3
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n/an/an/an/a 676n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]-GTP gama S binding assay

Bioorg Med Chem Lett 14: 5867-72 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.028
BindingDB Entry DOI: 10.7270/Q2XW4J94
More data for this
Ligand-Target Pair