Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50170328'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170328 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C26H33N5O2/c1-5-7-22-21-14-15-31(18-26(2,3)4)23(21)12-13-24(22)33-17-6-16-32-20-10-8-19(9-11-20)25-27-29-30-28-25/h8-15H,5-7,16-18H2,1-4H3,(H,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.54E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
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