Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50279772 (2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | PubMed | 3.72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Tested for binding affinity against Metabotropic glutamate receptor 2 in CHO cells using [3H]-7 as radioligand | J Med Chem 43: 4893-909 (2000) BindingDB Entry DOI: 10.7270/Q24J0DC8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50279772 (2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to block 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in non-neuronal cell line expressing human Metabotropic glutamate r... | J Med Chem 41: 346-57 (1998) Article DOI: 10.1021/jm970497w BindingDB Entry DOI: 10.7270/Q22F7MJ0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50279772 (2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 50.3 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Antagonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated in presence of 30 microM glutamic acid | J Med Chem 43: 4893-909 (2000) BindingDB Entry DOI: 10.7270/Q24J0DC8 | |||||||||||
More data for this Ligand-Target Pair |