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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4 (mGluR4)' and Ligand = 'BDBM50358187'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50358187
PNG
(CHEMBL1921960)
Show SMILES Oc1c2[C@H]3CC[C@H](O3)c2c(O)n1-c1ccc(NC(=O)c2ccccn2)cc1Cl |r,wU:6.6,3.7,(26.11,-24.74,;25.8,-23.23,;26.83,-22.09,;28.36,-22.11,;29.14,-20.79,;28.38,-19.45,;26.86,-19.44,;26.84,-20.97,;26.08,-20.75,;24.57,-21.05,;23.43,-20.01,;24.4,-22.59,;23.08,-23.39,;21.73,-22.64,;20.42,-23.44,;20.44,-24.98,;19.12,-25.77,;17.77,-25.02,;17.75,-23.48,;16.45,-25.81,;16.48,-27.35,;15.16,-28.15,;13.81,-27.4,;13.79,-25.85,;15.11,-25.06,;21.79,-25.73,;23.11,-24.94,;24.46,-25.68,)|
Show InChI InChI=1S/C20H16ClN3O4/c21-11-9-10(23-18(25)12-3-1-2-8-22-12)4-5-13(11)24-19(26)16-14-6-7-15(28-14)17(16)20(24)27/h1-5,8-9,14-15,26-27H,6-7H2,(H,23,25)/t14-,15+
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.30E+3n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay


J Med Chem 54: 7639-47 (2011)


Article DOI: 10.1021/jm200956q
BindingDB Entry DOI: 10.7270/Q25Q4WHD
More data for this
Ligand-Target Pair