Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Methionine synthase' and Ligand = 'BDBM50392650'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine synthase (Homo sapiens (Human))	BDBM50392650 (CHEMBL2153704) Show SMILES Nc1nc(N)c2N3CN(CC3CCc2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O |r| Show InChI InChI=1S/C21H25N7O5/c22-18-17-14(25-21(23)26-18)6-5-13-9-27(10-28(13)17)12-3-1-11(2-4-12)19(31)24-15(20(32)33)7-8-16(29)30/h1-4,13,15H,5-10H2,(H,24,31)(H,29,30)(H,32,33)(H4,22,23,25,26)/t13?,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of methionine synthase in human HL60 cells using L-homocysteine as substrate incubated for 3 hrs prior to substrate addition measured afte...				Eur J Med Chem 58: 228-36 (2012) Article DOI: 10.1016/j.ejmech.2012.09.027 BindingDB Entry DOI: 10.7270/Q2RX9D5C
					More data for this Ligand-Target Pair