Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Mineralocorticoid receptor' and Ligand = 'BDBM50439607'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50439607 (CHEMBL2419301) Show SMILES CC1NC(=O)C(=C1c1cc(C)c2OCC(=O)Nc2c1)c1ccc(F)cc1 |c:5| Show InChI InChI=1S/C20H17FN2O3/c1-10-7-13(8-15-19(10)26-9-16(24)23-15)17-11(2)22-20(25)18(17)12-3-5-14(21)6-4-12/h3-8,11H,9H2,1-2H3,(H,22,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [3H]aldosterone from human mineralocorticoid receptor expressed in 293 cells after 16 hrs by scintillation counting				Bioorg Med Chem 22: 5428-45 (2014) Article DOI: 10.1016/j.bmc.2014.07.038 BindingDB Entry DOI: 10.7270/Q218383G
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50439607 (CHEMBL2419301) Show SMILES CC1NC(=O)C(=C1c1cc(C)c2OCC(=O)Nc2c1)c1ccc(F)cc1 |c:5| Show InChI InChI=1S/C20H17FN2O3/c1-10-7-13(8-15-19(10)26-9-16(24)23-15)17-11(2)22-20(25)18(17)12-3-5-14(21)6-4-12/h3-8,11H,9H2,1-2H3,(H,22,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation counting				Bioorg Med Chem 21: 5983-94 (2013) Article DOI: 10.1016/j.bmc.2013.07.043 BindingDB Entry DOI: 10.7270/Q2TD9ZSH
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50439607 (CHEMBL2419301) Show SMILES CC1NC(=O)C(=C1c1cc(C)c2OCC(=O)Nc2c1)c1ccc(F)cc1 |c:5| Show InChI InChI=1S/C20H17FN2O3/c1-10-7-13(8-15-19(10)26-9-16(24)23-15)17-11(2)22-20(25)18(17)12-3-5-14(21)6-4-12/h3-8,11H,9H2,1-2H3,(H,22,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Antagonist activity at MR (unknown origin) expressed in COS1 cells after 1 day by luciferase reporter gene assay				Bioorg Med Chem 21: 5983-94 (2013) Article DOI: 10.1016/j.bmc.2013.07.043 BindingDB Entry DOI: 10.7270/Q2TD9ZSH
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50439607 (CHEMBL2419301) Show SMILES CC1NC(=O)C(=C1c1cc(C)c2OCC(=O)Nc2c1)c1ccc(F)cc1 |c:5| Show InChI InChI=1S/C20H17FN2O3/c1-10-7-13(8-15-19(10)26-9-16(24)23-15)17-11(2)22-20(25)18(17)12-3-5-14(21)6-4-12/h3-8,11H,9H2,1-2H3,(H,22,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Antagonist activity at human mineralocorticoid receptor expressed in COS1 cells after 1 day by luciferase reporter gene assay				Bioorg Med Chem 22: 5428-45 (2014) Article DOI: 10.1016/j.bmc.2014.07.038 BindingDB Entry DOI: 10.7270/Q218383G
					More data for this Ligand-Target Pair