Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM50115395'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50115395 (CHEMBL3608460) Show SMILES OC[C@@H](N1CCCn2cc(cc2C1=O)-c1ccnc(N[C@H]2CC[C@@H](O)C2)n1)c1ccccc1 |r| Show InChI InChI=1S/C25H29N5O3/c31-16-23(17-5-2-1-3-6-17)30-12-4-11-29-15-18(13-22(29)24(30)33)21-9-10-26-25(28-21)27-19-7-8-20(32)14-19/h1-3,5-6,9-10,13,15,19-20,23,31-32H,4,7-8,11-12,14,16H2,(H,26,27,28)/t19-,20+,23+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin)				Bioorg Med Chem Lett 25: 3788-92 (2015) Article DOI: 10.1016/j.bmcl.2015.07.091 BindingDB Entry DOI: 10.7270/Q2G44S3Q
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50115395 (CHEMBL3608460) Show SMILES OC[C@@H](N1CCCn2cc(cc2C1=O)-c1ccnc(N[C@H]2CC[C@@H](O)C2)n1)c1ccccc1 |r| Show InChI InChI=1S/C25H29N5O3/c31-16-23(17-5-2-1-3-6-17)30-12-4-11-29-15-18(13-22(29)24(30)33)21-9-10-26-25(28-21)27-19-7-8-20(32)14-19/h1-3,5-6,9-10,13,15,19-20,23,31-32H,4,7-8,11-12,14,16H2,(H,26,27,28)/t19-,20+,23+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	278	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of ERK2 in human A375 cells assessed as phosphorylated FRA level				Bioorg Med Chem Lett 25: 3788-92 (2015) Article DOI: 10.1016/j.bmcl.2015.07.091 BindingDB Entry DOI: 10.7270/Q2G44S3Q
					More data for this Ligand-Target Pair