Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM50166349'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50166349 (CHEMBL3799716) Show SMILES Clc1cccc(CNC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)c1 Show InChI InChI=1S/C42H44N6O6/c43-35(23-29-11-19-33(49)20-12-29)39(51)47-37(25-27-7-3-1-4-8-27)41(53)45-31-15-17-32(18-16-31)46-42(54)38(26-28-9-5-2-6-10-28)48-40(52)36(44)24-30-13-21-34(50)22-14-30/h1-22,35-38,49-50H,23-26,43-44H2,(H,45,53)(H,46,54)(H,47,51)(H,48,52)/t35-,36-,37-,38-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Green Valley Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged ERK2 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured aft...				Bioorg Med Chem Lett 26: 2600-4 (2016) Article DOI: 10.1016/j.bmcl.2016.04.029 BindingDB Entry DOI: 10.7270/Q2H99731
					More data for this Ligand-Target Pair