Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 1 (Homo sapiens (Human)) | BDBM50182212 (7-(4-fluorophenylamino)-1-((1S,3R)-3-hydroxycyclop...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffmann-La Roche Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Erk2 | Bioorg Med Chem Lett 16: 1950-3 (2006) Article DOI: 10.1016/j.bmcl.2005.12.092 BindingDB Entry DOI: 10.7270/Q2S46SRS | |||||||||||
More data for this Ligand-Target Pair |