Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 10' and Ligand = 'BDBM50332091'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50332091 (CHEMBL1288160 | N-(4,4'-bithiazol-5-yl)-2-(isoquin...) Show SMILES O=C(Cc1cccc2cnccc12)Nc1scnc1-c1cscn1 Show InChI InChI=1S/C17H12N4OS2/c22-15(6-11-2-1-3-12-7-18-5-4-13(11)12)21-17-16(20-10-24-17)14-8-23-9-19-14/h1-5,7-10H,6H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Elan Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant JNK3 after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 20: 7303-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.066 BindingDB Entry DOI: 10.7270/Q20865JW
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50332091 (CHEMBL1288160 | N-(4,4'-bithiazol-5-yl)-2-(isoquin...) Show SMILES O=C(Cc1cccc2cnccc12)Nc1scnc1-c1cscn1 Show InChI InChI=1S/C17H12N4OS2/c22-15(6-11-2-1-3-12-7-18-5-4-13(11)12)21-17-16(20-10-24-17)14-8-23-9-19-14/h1-5,7-10H,6H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01947 BindingDB Entry DOI: 10.7270/Q2CV4NSB
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50332091 (CHEMBL1288160 | N-(4,4'-bithiazol-5-yl)-2-(isoquin...) Show SMILES O=C(Cc1cccc2cnccc12)Nc1scnc1-c1cscn1 Show InChI InChI=1S/C17H12N4OS2/c22-15(6-11-2-1-3-12-7-18-5-4-13(11)12)21-17-16(20-10-24-17)14-8-23-9-19-14/h1-5,7-10H,6H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
IMAGO PHARMACEUTICALS, INC. US Patent					Assay Description (1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...				US Patent US9796706 (2017) BindingDB Entry DOI: 10.7270/Q24T6MHK
					More data for this Ligand-Target Pair